Research
The Science Behind COLASIL®
COLASIL® is built around stabilized orthosilicic acid, or OSA, a bioavailable form of silicon studied for its role in collagen formation and connective tissue health.*
Explore how OSA is stabilized, what each ingredient contributes, the documented patent history, and published research relevant to stabilized OSA and the formula’s approach.
A Different Approach to Collagen Support
Collagen is a structural protein found throughout the skin, joints, bones, tendons, ligaments, and other connective tissues. Collagen-containing tissues are also present around hair follicles and beneath nail beds. Supporting these structures is part of caring for how you look and move as you age.*
COLASIL® does not rely on collagen peptides as its main ingredient. It places stabilized OSA at the center of a daily formula designed to support the body’s natural collagen-forming process.*
Formula Transparency
How Each Ingredient Fits the Formula
Stabilized OSA is the foundation of COLASIL®, supported by CoQ10, taurine, Bambusa vulgaris sprout extract, and marine-derived collagen used as part of the OSA stabilization system.
Stabilized Orthosilicic Acid
Stabilized OSA is the bioavailable form of silicon at the center of the COLASIL® collagen-support system.*
Coenzyme Q10
CoQ10 complements the formula and is widely studied for its role in normal cellular energy production.*
Taurine
Taurine is an amino sulfonic acid included as a supporting component within the overall formula.
Bambusa vulgaris Sprout Extract
Bambusa vulgaris sprout extract provides a botanical source of naturally occurring silica.
Marine-Derived Collagen
Marine-derived collagen is used as part of the OSA stabilization system. It is not included to provide a traditional serving of collagen peptides.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
What Is Orthosilicic Acid, or OSA?
Orthosilicic acid, or OSA, is a small, soluble form of silicon that is more readily absorbed than less-soluble or highly polymerized forms of silica.*
Because OSA can lose its soluble form, COLASIL® uses stabilized OSA to help keep it available for absorption within the finished formula. OSA has been studied in connection with normal collagen formation and connective-tissue biology.*
Find clear answers about stabilized OSA, collagen powders, marine-derived collagen, what COLASIL® supports, and how to take it.
Common Questions About COLASIL®
Can You Take COLASIL® With Collagen Powder?
COLASIL® and collagen powders provide different nutritional inputs. Collagen powders primarily provide collagen-derived peptides and amino acids, while COLASIL® provides stabilized OSA, a bioavailable form of silicon studied in connection with collagen formation and connective-tissue biology.*
Some people may choose to use both. Review both product labels and speak with a qualified healthcare professional before combining supplements if you take medication, have a medical condition, or are pregnant or nursing. COLASIL® contains fish and should not be used by anyone with a fish allergy.
What Is the Difference Between Silica and Collagen?
Collagen is a structural protein found throughout the skin, joints, bones, and connective tissue. Silica contains silicon, while OSA is a soluble, bioavailable form of silicon studied in connection with collagen formation. They are not the same ingredient and provide different nutritional inputs.*
COLASIL® centers on stabilized OSA rather than providing collagen peptides as its main ingredient.*
What Does COLASIL® Support?
COLASIL® is designed to support the body’s natural collagen-forming process and connective-tissue structures associated with the skin, joints, bones, hair follicles, and nail beds.*
Human research on specific stabilized OSA preparations has reported findings related to skin properties and the strength of hair and nails. Broader research has examined silicon in connection with bone and connective-tissue biology. These studies were not clinical trials of the finished COLASIL® formula.*
How Long Does It Take to Notice Results?
Results and timing will vary. Human studies of specific stabilized OSA preparations evaluated skin-related changes after approximately three to five months, while one hair study continued for nine months.
Take COLASIL® daily as directed and allow time for your body to respond. Individual results and timing cannot be guaranteed.
Is COLASIL® a Collagen Powder?
No. COLASIL® is a capsule-based collagen-support formula built around stabilized OSA, not a powder made primarily from collagen peptides.
Marine-derived collagen is used as part of the OSA stabilization system rather than to provide a traditional serving of collagen peptides. COLASIL® contains fish and is not vegan.
How Do You Take COLASIL®?
Take two COLASIL® capsules daily, with or without food. Choose a consistent time that fits your routine so daily use is easy to maintain.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Patent History Relevant to Stabilized OSA
The stabilization approach used in COLASIL® is connected to an international patent family involving stable, bioavailable orthosilicic acid complexes.
These patents document the development of OSA stabilization systems and provide technical context for the approach used in the COLASIL® formula.
Referenced Patents
EP1092728 · US6335457 · FR2799758 · DE60028152 · CN1202130 · BR0004827 · AR026030 · MXPA00010013 · AU774668 · JP4729161
Published Research on OSA,
Silicon and Collagen Biology
These publications provide scientific context for understanding how orthosilicic acid and silicon have been studied in relation to collagen formation, bone biology, and connective-tissue health.
Reffitt DM, Ogston N, Jugdaohsingh R, et al.
Orthosilicic acid stimulates collagen type I synthesis and osteoblastic differentiation in human osteoblast-like cells in vitro.
Bone. 2003;32(2):127–135.
Spector TD, Calomme MR, Anderson SH, et al.
Choline-stabilized orthosilicic acid supplementation as an adjunct to calcium/vitamin D3 stimulates markers of bone formation in osteopenic women: a randomized controlled trial.
BMC Musculoskeletal Disorders. 2008;9:85.
Jugdaohsingh R.
Silicon and bone health.
Journal of Nutrition, Health & Aging. 2007;11(2):99–110.
Further Reading on OSA and Collagen Structure
This research overview brings together published literature on silicon biology, orthosilicic acid stabilization, collagen formation, and connective-tissue structure. It provides a closer look at the research relevant to stabilized OSA and its role in collagen support.*
Ready to Begin Your COLASIL® Routine?
Choose the bottle that fits your routine and begin with confidence.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.